Journal
AUTOIMMUNITY REVIEWS
Volume 10, Issue 7, Pages 410-415Publisher
ELSEVIER
DOI: 10.1016/j.autrev.2011.01.005
Keywords
Mesenchymal stem cells; Cellular therapy; Immunomodulation; Autoimmune diseases; Multiple sclerosis; Myasthenia gravis
Categories
Funding
- European Union [242210]
Ask authors/readers for more resources
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent progenitor cells which can be isolated from various human adult tissues. In recent years. MSCs have been shown to possess broad immunoregulatory capabilities, modulating both adaptive and innate immunity. This review discusses the documented immunomodulatory capabilities of the MSCs, the possible mechanisms underlying these functions and presents the potential of using this stem cell-based approach as an immunomodulatory tool for the treatment of autoimmune diseases. (C) 2011 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available