Journal
ADVANCED DRUG DELIVERY REVIEWS
Volume 53, Issue 1, Pages 23-44Publisher
ELSEVIER
DOI: 10.1016/S0169-409X(01)00219-8
Keywords
biodegradable; block copolymer; star-block copolymer; poly(esters); poly(ether-b-ester); poly(ether ester amide); surface modification; micelles; hydrogels; nanoparticles; microparticles; drug-targeting
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Recently, block copolymers have got tremendous impetus on the ongoing research in the area of drug delivery technology, due to their capability to provide a biomaterial having a broad range of amphiphilic characteristics, as well as targeting the drugs to specific site. This article is an attempt to review applications of block copolymers in surface modification, drug targeting, nano and microparticles, hydrogels, micelles etc. The physicochemical properties of block copolymers and various synthetic routes for block copolymers are also discussed. (C) 2001 Elsevier Science B.V. All rights reserved.
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