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Enhanced chromatographic resolution of alcohol enantiomers as phosphate or phosphonate derivatives

TETRAHEDRON-ASYMMETRY (2001)

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Journal

TETRAHEDRON-ASYMMETRY
Volume 12, Issue 22, Pages 3063-3066

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0957-4166(01)00556-0

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Categories

Chemistry, Inorganic & Nuclear Chemistry, Organic Chemistry, Physical

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Phosphate and phosphonate derivatives of chiral alcohols show enhanced resolution by HPLC using a chiral support. Labile derivatives were also prepared that allow separation and recovery of the corresponding alcohol after basic hydrolysis. (C) 2002 Elsevier Science Ltd. All rights reserved.

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