Journal
ONCOGENE
Volume 20, Issue 58, Pages 8308-8316Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.onc.1205091
Keywords
E-proteins; bHLH; Id
Ask authors/readers for more resources
Helix - loop - helix (HLH) proteins are essential factors for lymphocyte development and function. One class of HLH proteins, the E-proteins, regulate many aspects of lymphocyte maturation, survival, proliferation, and differentiation. E-proteins are negatively regulated by another class of HLH proteins known as the Id proteins. The Id proteins function as dominant negative inhibitors of E-proteins by inhibiting their ability to bind DNA. Here we discuss the function and regulation of the Id proteins in lymphocyte development.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available