4.8 Article

Highly efficient and catalytic conversion of aldoximes to nitriles

Journal

ORGANIC LETTERS
Volume 3, Issue 26, Pages 4209-4211

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0168768

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[GRAPHICS] Catalytic dehydration of aldoximes can be performed highly efficiently with a catalyst system of [RuCl2(p-cymene)](2)/molecular sieves under essentially neutral and mild conditions, and various types of cyano compounds are produced in good to excellent yields.

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