4.5 Article

Bromonium ion-promoted glycosidic bond formation and simultaneous bromination of an activated aryl aglycon

Journal

CARBOHYDRATE RESEARCH
Volume 337, Issue 1, Pages 31-36

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/S0008-6215(01)00276-2

Keywords

N-bromosuccinimide; thioglycoside; bromination

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N-Bromosuccinimide (NBS) together with a catalytic amount of Me3SiOTf was found to be effective for the activation of thioglycosides. Concurrently with formation of the glycosidic bond, bromination took place on the activated aromatic ring of a 4-methoxyphenyl aglycon. (C) 2002 Elsevier Science Ltd. All rights reserved.

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