4.5 Article

A model for odour thresholds

Journal

CHEMICAL SENSES
Volume 27, Issue 2, Pages 95-104

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/chemse/27.2.95

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Funding

  1. NIDCD NIH HHS [R 29 DC 02741, R 01 DC 02741] Funding Source: Medline

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Odour detection thresholds, that we have previously obtained, have been analysed by a general equation for selective transport. It is shown that such selective transport can account for some 77% of the total effect. The remainder is due to a specific size effect, that might involve odour-binding proteins, and a specific effect for aldehydes and carboxylic acids. Our analysis raises the question of whether selective transport is physically separable from the specific effects of receptor activation. The model predicts a chemical cut-off in odour detection along any homologous series.

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