Journal
JOURNAL OF ARTHROPLASTY
Volume 30, Issue 12, Pages 2185-2189Publisher
CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS
DOI: 10.1016/j.arth.2015.06.026
Keywords
total knee arthroplasty; bone mineral density; fracture risk; osteoporosis; risk adjustment
Categories
Funding
- Alberta Innovates Health Solutions
- Canadian Institutes for Health Research
- University Hospital Foundation
- Alberta Arthroplasty Research Group
- Alberta Innovates [201400391] Funding Source: researchfish
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This study evaluated age-and sex-adjusted changes in total hip and spine bone mineral density (BMD) within 1 year of total knee arthroplasty (TKA) using a prospective, longitudinal cohort with a one-year follow-up. Preoperatively, subjects underwent routine bone mineral densitometry of their hip and spine, which was repeated 12 months postoperatively. Of 108 subjects, 97 (90%) completed BMD testing. Total hip BMD decreased significantly over time (1.80% change, P < 0.001) with females losing more than males (P < 0.001). The pattern was similar, but attenuated in the spine. Subjects undergoing primary cemented TKA had significant bone loss in the hip within 12 months, beyond that expected with age. (C) 2015 Elsevier Inc. All rights reserved.
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