Journal
NATURE REVIEWS GENETICS
Volume 3, Issue 2, Pages 124-136Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg730
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Molecular genetic studies rely on well-characterized organisms that can be easily manipulated. Arabidopsis thaliana - the model system of choice for plant biologists - allows efficient analysis of plant function, combining classical genetics with molecular biology. Although the complete sequence of the Arabidopsis genome allows the rapid discovery of the molecular basis of a characterized mutant, functional characterization of the Arabidopsis genome depends on well-designed forward genetic screens, which remain a powerful strategy to identify genes that are involved in many aspects of the plant life cycle.
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