Journal
DIGESTIVE AND LIVER DISEASE
Volume 34, Issue 2, Pages 144-150Publisher
PACINI EDITORE
DOI: 10.1016/S1590-8658(02)80246-8
Keywords
portal blood flow; splanchnic circulation; splenectomy; splenomegaly
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The possible relationships between splenomegaly and portal hypertension have been analysed in patients with cirrhosis. In this condition, splenomegaly is not only caused by portal congestion, but it is mainly due to tissue hyperplasia and fibrosis. The increase in spleen size is followed by an increase in splenic blood flow, which participates in portal hypertension actively congesting the portal system.
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