Journal
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
Volume 116, Issue 1, Pages 5-11Publisher
SPRINGER-VERLAG
DOI: 10.1007/s004140100239
Keywords
capillary electrophoresis; forensic science; artificial neural networks; post-mortem interval; vitreous humour
Categories
Ask authors/readers for more resources
Determination of electrolyte concentrations (mainly potassium) in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval (PMI). On the basis of its well known potential in ion analysis, capillary zone electrophoresis (CZE) has recently been applied to achieve a rapid and simultaneous determination of inorganic ions in this extracellular fluid. In the present work, artificial neural networks (ANN) were applied for modelling of the relationship of multicomponent CZE analysis of K+, NH4+, Na+, and Ba2+ ions in vitreous humour with PMI. In a study based on 61 cases with different causes of death and a known PMI ranging from 3 to 144 11, the use of ANNs considering all inorganic ion data from the human vitreous humour, achieved a substantial improvement of post-mortem interval prediction. Good linear correlation was observed (r(2) = 0.98) and in comparison to the traditional linear least squares (LLS) method applied only to K I levels in the vitreous humour, the prediction of PMI with ANN was improved by a factor of 5 from 15 h to less than 3 h.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available