Journal
MOLECULAR CELL
Volume 9, Issue 2, Pages 213-224Publisher
CELL PRESS
DOI: 10.1016/S1097-2765(02)00443-4
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- NCI NIH HHS [CA-84941] Funding Source: Medline
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CtBP family proteins are conserved among vertebrates and invertebrates and function as transcriptional corepressors. They repress transcription in a histone deacetylase-dependent or -independent manner. CtBPs play important roles during development and oncogenesis. In this review, their unusual properties, the mechanisms of transcriptional repression, regulation, and their biological functions are discussed.
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