4.4 Article

InCl3 and In(OTf)3 catalyzed reactions:: synthesis of 3-acetyl indoles, bis-indolylmethane and indolylquinoline derivatives

Journal

TETRAHEDRON
Volume 58, Issue 6, Pages 1229-1232

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(01)01227-3

Keywords

indium trichloride; indium triflate; acetylation; 3-acetyl indoles; bis-indolylmethane

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Indium trichloride and indium triflate were found to be effective catalysts for the acetylation of indoles to 3-acetyl indoles and is reported for the first time in good yield. Indium triflate is also found to be an efficient catalyst for the synthesis of bis-indolylmethane and indolylquinoline derivatives. (C) 2002 Elsevier Science Ltd. All rights reserved.

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