Journal
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Volume 16, Issue 5-6, Pages 217-222Publisher
ELSEVIER
DOI: 10.1016/S1381-1177(01)00064-9
Keywords
epoxide hydrolases; enzymatic resolution; Aspergillus niger; pyridyloxirane; screening
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A study aimed to select efficient epoxide hydrolases (EHs) allowing to achieve the enzymatic resolution of 2-, 3- and 4-pyridyloxirane (1-3) has been achieved, using 2-pyridyloxirane I as test substrate. Five thus selected EH-sources that showed interesting enantioselectivity were looked at in more detail for the conversion of 1-3. (C) 2002 Elsevier Science B.V. All rights reserved.
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