Journal
CELL
Volume 108, Issue 4, Pages 513-521Publisher
CELL PRESS
DOI: 10.1016/S0092-8674(02)00650-5
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Recent developments in live-cell imaging are challenging our stereotyped view of the fixed cell nucleus. The emerging picture is that nuclear processes may rely on a constant flow of molecules between dynamic compartments created by relatively immobile binding or assembly sites. This article discusses current views on the origins of nuclear compartments and their roles in gene expression.
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