Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 67, Issue 5, Pages 1712-1715Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo011076w
Keywords
-
Categories
Ask authors/readers for more resources
2-Substituted acetophenones such as 2-cyano-, 2-azido-, or 2-nitroacetophenones were effectively reduced with a mixture of HCOOH/N(C2H5)(3) containing a chiral Ru-(II) catalyst, RuCl[(S,S)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine](p-cymene), giving the corresponding optically active alcohols, which can be converted to optically active amino alcohols with excellent ee's. Similarly, the reaction of 2-benzoylacetophenone with the same Ru catalyst gave a quantitative yield of the corresponding optically active 1,3-diol with 99% ee.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available