Journal
TETRAHEDRON LETTERS
Volume 43, Issue 12, Pages 2157-2159Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)00222-8
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Optimum conditions for the preparation of aryl-alkyl ethers from N-protected aminoalcohols using polymer-supported triphenylphosphine have been developed. In contrast to previous literature reports, it was discovered that the progress of this reaction is greatly improved when a tertiary amine base is employed, along with minor modifications being made to the order of reagent addition. (C) 2002 Elsevier Science Ltd. All rights reserved.
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