Journal
TETRAHEDRON
Volume 58, Issue 13, Pages 2529-2532Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(02)00132-1
Keywords
alpha-amino nitriles; one-pot three-component condensation; indium trichloride
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A simple and general method has been developed for the synthesis of alpha-aminonitriles by a one-pot three-component condensation of aldehydes or ketones, amines and potassium cyanide in THF in presence of a catalytic amount of indium trichloride. (C) 2002 Elsevier Science Ltd. All rights reserved.
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