Journal
TETRAHEDRON LETTERS
Volume 43, Issue 13, Pages 2427-2430Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)00290-3
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alpha-Keto acid esters can be easily prepared in high yields in two steps from terminal alkynes via bromination and oxidation. This strategy provides a versatile access to the synthesis of biologically important natural products with an alpha-keto acid moiety. (C) 2002 Elsevier Science Ltd. All rights reserved.
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