4.4 Article

Coactivators in transcription initiation: here are your orders

Journal

CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 12, Issue 2, Pages 149-155

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(02)00280-0

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Coactivators are diverse and multifunctional proteins that act downstream of DNA-binding activators to stimulate transcription. Recent studies elucidate the temporal sequence in which coactivators are recruited to target promoters, and how their enzymatic properties and molecular interactions culminate in transcriptional initiation.

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