4.6 Review

Multi-state models for event history analysis

Journal

STATISTICAL METHODS IN MEDICAL RESEARCH
Volume 11, Issue 2, Pages 91-115

Publisher

ARNOLD, HODDER HEADLINE PLC
DOI: 10.1191/0962280202SM276ra

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Funding

  1. NCI NIH HHS [R01-CA54706-09] Funding Source: Medline

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An introduction to event history analysis via multi-state models is given. Examples include the two-state model for survival analysis, the competing risks and illness-death models, and models for bone marrow transplantation. Statistical model specification via transition intensities and likelihood inference is introduced. Consequences of observational patterns are discussed, and a real example concerning mortality and bleeding episodes in a liver cirrhosis trial is discussed.

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