Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 13, Issue 2, Pages 117-123Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0958-1669(02)00300-2
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In recent years, the number of recombinant proteins used for therapeutic applications has increased dramatically. Many of these applications involve complex glycoproteins and antibodies with relatively high production needs. These demands have driven the development of a variety of improvements in protein expression technology, particularly involving mammalian and microbial culture systems.
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