Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 14, Issue 2, Pages 167-172Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(02)00313-7
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Funding
- NIA NIH HHS [AG 15430] Funding Source: Medline
- NIGMS NIH HHS [GM 57464, R01 GM057464] Funding Source: Medline
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A new generation of live-cell fluorescent biosensors enables us to go beyond visualization of protein movements, to quantify the dynamics of many different protein activities. Alternate approaches can report post-translational modifications, ligand interactions and conformational changes, revealing how the location and subtle timing of protein activity controls cell behavior.
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