Journal
NEUROSCIENTIST
Volume 8, Issue 2, Pages 89-92Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/107385840200800204
Keywords
pain; transmitter release; dorsal root ganglia
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Funding
- NINDS NIH HHS [NS38680, NS30888, R01 NS030888] Funding Source: Medline
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Sensory neurons, in particular the small- and medium-diameter cells that sense painful stimuli, express both ionotropic and metabotropic glutamate receptors, which may regulate transmission between sensory neurons and their targets in the spinal cord dorsal horn. Although the roles that these receptors play in normal physiology are not completely understood, recent work has provided strong evidence for their ability to modulate transmitter release from primary afferent terminals.
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