Journal
NEUROPSYCHOPHARMACOLOGY
Volume 26, Issue 4, Pages 431-443Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0893-133X(01)00344-X
Keywords
serotonin; dopamine; behavior; personality; macaque; aggression
Categories
Funding
- NHLBI NIH HHS [HL 40962, HL 45666] Funding Source: Medline
- NIMH NIH HHS [MH 46745] Funding Source: Medline
Ask authors/readers for more resources
Social dominance is a fundamental component of both human and nonhuman primate sociality. However, its neurobiological correlates remain incompletely understood, We evaluated the association between dominance status and monoamine Metabolite concentrations in cisternal cerebrospinal fluid (CSF) in adult male (n = 25) and female (n = 21) cynomolgus macaques (Macaca fascicularis) housed in unisexual social groups. Concentrations of the metabolites of dopamine (homovanillic acid [HVA]), norepinephrine (3-methoxy-4-hydroxyphenylglycol [MHPG]) and serotonin (5-hydroxyindoleacetic acid [5-HIAA]) were assayed. Dominant monkeys, both males and females, had significantly higher CSF HVA concentrations than did subordinates (p values <.05). Among values, but not females, dominants also had lower CSF 5-HIAA than subordinates (P <.05). The Dominance-HVA association observed here is consistent with recent speculation that social extraversion, a dominance-related personality trait in humans, may also reflect heightened central nervous system dopaminergic activity. (C) 2002 American College of Neuropsychopharmacology. Published by Elsevier Science Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available