Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 25, Issue 2, Pages 154-157Publisher
PHARMACEUTICAL SOCIETY KOREA
DOI: 10.1007/BF02976556
Keywords
Foeniculum vulgare; dillapional; scopoletin; dillapiol; bergapten; imperatorin; psolaren; antimicrobial activity
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A phenyl propanoid derivative, dillapional(1) was found to be a antimicrobial principle of the stems of Foeniculum vulgare (Umbelliferae) with MIC values of 125, 250 and 125/ against Bacillus subtilis, Aspergillus niger and Cladosporium cladosporioides, respectively. A coumarin derivative, scopoletin(2) was also isolated as marginally antimicrobial agent along with inactive compounds, dillapiol(3), bergapten(4), imperatorin(5) and psolaren(6) from this plant. The isolates 1-6 were not active against the Escherichia coli.
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