A novel palladium-catalyzed homocoupling reaction initiated by transmetallation of palladium enolates

Palladium-catalyzed homocoupling reaction of aryl boronic acids has been developed using a protocol similar to the well-documented crosscoupling reaction. alpha-Hatocarbonyl compounds are applied to initiate the reaction via oxidative addition to a palladium(0) species. The resulting palladium enolate halide can promote the double transmetallation. Reductive elimination generates the desire homocoupling product. (C) 2002 Elsevier Science Ltd. All rights reserved.