Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 6, Issue 2, Pages 187-192Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S1367-5931(02)00295-8
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Recent data demonstrate that transition metal ions such as copper not only bind the priors protein with high affinities, but also modify its biochemical properties. This has important consequences for the potential function of the protein in metal-ion transport or as an anti-oxidant molecule. In addition, this relationship between the priors protein and metal ions is likely to play a critical role in the physiopathology of priors diseases.
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