Declining ambient air pollution and lung function improvement in Austrian children

Three thousand four hundred fifty-one Austrian elementary school children were examined (between 2 and 8 times) by spirometry by standardized methods, over a 5 yr period. The districts where they lived were grouped into those where NO2 declined during this period (by at least 30 mug/m(3) measured as half year means) and those with less or no decline in ambient NO2. In both groups of districts, SO2 and TSP fell by similar amounts over this period. A continuous improvement of MEF25 (maximum exspiratory flow rate at 25% vital capacity) was found in districts with declining ambient NO2. Populations did not differ in respect of anthropometric factors, passive smoking or socioeconomic status. A birth cohort from this study population which was followed up to age 18 confirmed the improved growth of MEF25 with decline in NO2, while the improved growth of forced vital capacity was more related to decline in SO2. This study provides the first evidence that improvements in the outdoor air quality during the 1980s are correlated with health benefits, and suggest that adverse effects on lung function related to ambient air pollution are reversible before adulthood. Improvement of small airway functions appeared to be more dependent on reductions of NO2 than reduction in SO2 and TSP. (C) 2002 Elsevier Science Ltd. All rights reserved.