Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 6, Issue 2, Pages 217-223Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S1367-5931(02)00314-9
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Funding
- NCRR NIH HHS [P41RR09793] Funding Source: Medline
- NIGMS NIH HHS [R01GM29754] Funding Source: Medline
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NMR spectroscopy and X-ray crystallography in conjunction with extended X-ray absorption fine structure spectroscopy, have contributed to the elucidation of the structural biology of protein-mediated mechanisms of heavy metal homeostasis. Among the most striking aspects of these investigations are the remarkable similarity of metal-ion-transport and sequestering systems across different species, and the need to continue the research to confirm hypotheses for the molecular mechanisms of transfers of metal ions between proteins.
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