Journal
NATURE NEUROSCIENCE
Volume 5, Issue 4, Pages 364-370Publisher
NATURE AMERICA INC
DOI: 10.1038/nn817
Keywords
-
Categories
Funding
- NEI NIH HHS [EY30164] Funding Source: Medline
- NIMH NIH HHS [T32 MH020016] Funding Source: Medline
Ask authors/readers for more resources
We describe a compelling demonstration of large-scale developmental reorganization in the human visual pathways. The developmental reorganization was observed in rod monochromats, a rare group of congenitally colorblind individuals who virtually lack cone photoreceptor function. Normal controls had a cortical region, spanning several square centimeters, that responded to signals initiated in the all-cone foveola but was inactive under rod viewing conditions; in rod monochromats this cortical region responded powerfully to rod-initiated signals. The measurements trace a causal pathway that begins with a genetic anomaly that directly influences sensory cells and ultimately results in a substantial central reorganization.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available