Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 6, Issue 2, Pages 145-150Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1367-5931(02)00297-1
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Lipases are the most used enzymes in synthetic organic chemistry, catalyzing the hydrolysis of carboxylic acid esters in aqueous medium or the reverse reaction in organic solvents. Recent methodological advancements regarding practical factors affecting lipase activity and enantioselectivity are reviewed. Select practical examples concerning the use of lipases in the production of chiral intermediates are also highlighted.
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