Journal
JOURNAL OF GENERAL VIROLOGY
Volume 83, Issue -, Pages 801-805Publisher
SOC GENERAL MICROBIOLOGY
DOI: 10.1099/0022-1317-83-4-801
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Two full-length human immunodeficiency virus type 1 O sequences are described, one of which was hypermutated in all regions of the genome. This indicates that the intracellular [dTTP]/[dCTP] bias conducive to G --> A hypermutation may be sustained throughout the synthesis of minus-strand DNA. In turn, this suggests the possibility of mutation of host sequences.
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