4.8 Article

Regioselective synthesis of 3-alkynyl-5-bromo-2-pyrones via Pd-catalyzed couplings on 3,5-dibromo-2-pyrone

Journal

ORGANIC LETTERS
Volume 4, Issue 7, Pages 1171-1173

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol025613q

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[GRAPHICS] 3,5-Dibromo-2-pyrone underwent facile Pd(0)-catalyzed coupling reactions with various alkynes to give rise to the corresponding 3-alkynyl-5-bromo-2-pyrones with good to excellent chemical yields and regioselectivity.

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