Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 952, Issue 1-2, Pages 1-11Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0021-9673(00)00176-X
Keywords
reviews; stationary phases, LC; surface modification; supports; alumina
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This review begins by describing the relevant properties or alumina as a support material for chemically bonded stationary phases in HPLC. The most common chemical modification processes are summarized as well as the advantages and disadvantages of each method. In order to more fully understand the chemically modified alumina surface. some spectroscopic approaches are outlined for characterization of the bonded phases. Finally. a number of successful applications are described for a variety of chemically modified aluminas in order to illustrate their potential usefulness and to compare their chromatographic behavior to the more conventional silica-based materials. (C) 2002 Elsevier Science B.V. All rights reserved.
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