Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 952, Issue 1-2, Pages 139-147Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0021-9673(02)00088-2
Keywords
tandem mass spectrometry; electrospray ionization; acidic drugs
Ask authors/readers for more resources
A liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS-MS) method was developed and validated for simultaneous analysis of nine acidic pharmaceutical drugs (bezafibrate. clofibric acid, diclofenac, fenoprofen, gemfibrozil, ibuprofen, indomethacin, ketoprofen and naproxen) in sewage treatment plant (STP) effluents. The mean recoveries of the pharmaceuticals ranged front 58.9 to 91.5% in STP effluent. and the limits of detection of the analytes were 5-20 ng/ml. The method was applied to the quantitative analysis of acidic drugs in the effluents from three Canadian STPs, in which bezafibrate, diclofenac. fenoprofen, gemfibrozil, ibuprofen. indomethacin and naproxen were detected. (C) 2002 Published by Elsevier Science B.V.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available