4.4 Article

A novel synthesis of 5-hydroxy-2,2-dimethyl-10-propyl-2H-pyrano[2,3-f]chromen-8-one

Journal

TETRAHEDRON LETTERS
Volume 43, Issue 16, Pages 2899-2902

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)00428-8

Keywords

selective desulfonation; chromene synthesis; calanolide A

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A concise synthesis of 5-hydroxy-2.2-dimethyl-10-propyl-2H-pyrano[2.3-f]chromen-8-one utilising a novel selective desulfonylation protocol is described. This method provides facile access to a key intermediate for the asymmetric synthesis of calanolide A. (C), 2002 Elsevier Science Ltd. All rights reserved.

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