Journal
AUSTRALASIAN JOURNAL OF DERMATOLOGY
Volume 54, Issue 1, Pages E25-E27Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1440-0960.2011.00818.x
Keywords
etretinate; oral erosive lichen planus; thymoma
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A 68-year-old Japanese woman was referred to our hospital with a 1-year history of multiple erosions on the oral mucosa and a few pruritic, bean-sized, reddish-blue plaques on the body. Based on physical examination, pathological findings, and immunofluorescence findings, a diagnosis of lichen planus (LP) was made. Computed tomography scan revealed a thymoma. After thymectomy, cutaneous LP lesions subsided spontaneously. Oral lesions responded well to oral etretinate therapy. We speculate that direct tissue injury by CD8+ T cells, activated by abnormal regulation of lymphocytes within the thymus, may cause LP.
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