Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 12, Issue 8, Pages 1163-1166Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(02)00112-9
Keywords
-
Categories
Ask authors/readers for more resources
Honokiol. a main biphenyl neolignan of the traditional crude medicine, Magnoliae cortex, as found to show neurotrophic activity on the cultures of rat cortical neurons at concentration from 0.1 to 10 muM. In the cortical neurons cultured in serum-free medium Supplemented with B27, honokiol could promote neurite outgrowth. In addition, the survival and growth of neurons were significantly enhanced by adding honokiol to the primary cultures in serum-free medium supplemented with N2, Its neurotrophic activity was comparable to 40 ng mL(-1) of bFGF at concentration of 10 muM. (C) 2002 Elseier Science Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available