Journal
NEUROLOGY
Volume 58, Issue 8, Pages 1294-1296Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.58.8.1294
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Funding
- NCRR NIH HHS [5 M01 RR00044] Funding Source: Medline
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As a first step toward understanding which changes should be considered as meaningful, the authors assessed the reliability of quantitative functional tests on 5 consecutive days in 63 patients with MS, determining the range of measurement variability present when patients are clinically,table. Time to walk 25 feet (T25FW) and the 9-hole peg test (9HPT) varied by <20%, of individual mean scores on repeated testing. Therefore, a 20% change on these tests can be considered to be the threshold that reliably indicates a true change in function for an individual.
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