Journal
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Volume 444, Issue 1-2, Pages 1-25Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00424-002-0805-1
Keywords
RVD; VSOAC; VRAC; I-Cl,I-vol; I-Cl,I-swell; ORCC; RVDC; swelling
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The ability of cells to readjust their volume after swelling, a phenomenon known as regulatory volume decrease (RVD), is a fundamental biological achievement guaranteeing survival and function of cells under osmotic stress. This article reviews the mechanisms of RVD in mammalian cells with special emphasis on the activation of ion channels during RVD.
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