Journal
MECHANISMS OF DEVELOPMENT
Volume 113, Issue 2, Pages 211-214Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0925-4773(02)00033-3
Keywords
lens; CAP1; cyclase associated proteins; Xenopus laevis; branchial arch; ocular mesenchyme; sensorial ectoderm; pronephros; act up
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We have cloned and characterized a Xenopus member of the cyclase associated protein (CAP) gene family. xCAP1 is expressed as a maternal transcript, but is up-regulated prior to gastrulation and subsequently localizes to head mesenchyme, lens, otic vesicle, and trunk mesoderm including the pronephros. At different stages, the gone also appears to differentiate surface from deep (sensorial) ectoderm. As in Drosophila, Xenopus CAP1 is expressed in the developing eye, specifically in the differentiating lens. However, in distinction to Drosophila, Xenopus CAP1 does not express in periodically arrayed neural bands. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
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