Journal
PHARMACOLOGICAL RESEARCH
Volume 45, Issue 5, Pages 361-368Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1006/phrs.2002.0969
Keywords
glucocorticoids; immunomodulation
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The development and function of cells in the immune system are regulated by many intrinsic and extrinsic factors. One class of molecule that affects immune cells belongs to the neuroendocrine system and the best-studied mediators in this category are glucocorticoids. These are small lypophilic molecules that participate in a wide number of normal and pathologic processes. This paper concentrates on their physiologic and pharmacologic effects on the immune response. (C) 2002 Elsevier Science Ltd. All rights reserved.
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