Two 8C-methylated flavonols from the leaves of Vellozia candida Mikan (Velloziaceae)

From the leaves of Vellozia candida Mikan (Velloziaceae) the new flavonol 3',4',5,7-tetrahydroxy-3,6-dimethoxy-8-methylflavone and its known 7-O-methyl derivative, 3',4',5-trihydroxy-3,6,7-trimethoxy-8-methylflavone, were isolated and characterized by spectral data, including 2D NMR and tandem mass spectrometry experiments. The 5-hydroxy-3,3', 4',6,7-pentamethoxy-8-methylflavone derivative was obtained by methylation with diazomethane.