Journal
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Volume 1575, Issue 1-3, Pages 135-138Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0167-4781(02)00236-1
Keywords
histamine; H4 receptor; GPCR; ortholog; porcine; cDNA cloning
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The cDNA encoding histamine H4 receptor was cloned from the porcine spleen cDNA library. Porcine H4 receptor, which shares 72% homology with its human counterpart. bound to histamine in receptor-expressing mammalian cells. Isolation of the porcine H4 receptor, which is important for understanding of the pharmacology, will aid in better interpretation of physiological role of this subtype of histamine receptor. (C) 2002 Elsevier Science B.V. All rights reserved.
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