4.8 Article

Diffusion tensor imaging in refractory epilepsy

Journal

LANCET
Volume 359, Issue 9319, Pages 1748-1751

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/S0140-6736(02)08615-4

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Funding

  1. Medical Research Council [G9805989] Funding Source: Medline
  2. Medical Research Council [G9805989] Funding Source: researchfish
  3. MRC [G9805989] Funding Source: UKRI

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Diffusion tensor Imaging Is an Imaging method that Is sensitive to the molecular movement of water, which Indicates cellular Integrity and pathology. A patient with refractory epilepsy and normal conventional MRI was examined with diffusion tensor Imaging. An area of abnormal diffusion In the right frontal lobe was Identified and surgically resected. The patient had a good clinical outcome. Histopathological examination of the resected tissue showed gliosis. Our findings may affect the Investigation of similar patients, and provide histopathological confirmation of diffusion abnormalities.

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