4.7 Article

One-step synthesis of α-pyrones from acyl chlorides by the Stille reaction

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 67, Issue 11, Pages 3941-3944

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo025518v

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Palladium-catalyzed stereoselective annulation of a functional vinylstannane by acyl chlorides gives the corresponding alpha-pyran-2-ones in good yields. This annulation most probably proceeds through a Stille reaction/cyclization sequence.

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