Journal
PSYCHIATRY AND CLINICAL NEUROSCIENCES
Volume 56, Issue 3, Pages 303-304Publisher
BLACKWELL PUBLISHING ASIA
DOI: 10.1046/j.1440-1819.2002.01006.x
Keywords
electroencephalogram; herbal medicine; human; polysomnography; Yoku-kan-san-ka-chimpi-hange
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Yoku-kan-san-ka-chimpi-hange (YKCH) is a drug used for insomnia in Japanese traditional herbal medicine. The present study evaluated the effects of YKCH on sleep by all-night polysomnography using the double-blind method. Yoku-kan-san-ka-chimpi-hange increased the total sleep time significantly, and tended to cause an increase in sleep efficiency and of stage 2 sleep, as well as a decrease of sleep latency and of stage 3 + 4 sleep. There was no apparent influence on rapid eye movement (REM) sleep. In terms of non-REM sleep, the effects of YKCH exhibit a profile similar to those of benzodiazepines.
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