Journal
MAGNETIC RESONANCE IN MEDICINE
Volume 47, Issue 6, Pages 1176-1185Publisher
WILEY-BLACKWELL
DOI: 10.1002/mrm.10162
Keywords
active surface; atrophy; spinal cord; multiple sclerosis
Funding
- Multiple Sclerosis Society [491] Funding Source: Medline
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A method is presented that aims at segmenting and measuring the surface of the spinal cord from MR images in order to detect and quantify atrophy. A semiautomatic segmentation with very little intervention from an operator is proposed. It is based on the optimization of a B-spline active surface. The method allows for the computation of orthogonal cross-sections at any level along the cord, from which measurements are derived, such as cross-sectional area or curvature. An evaluation of the accuracy and reproducibility of the method is presented.
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