4.5 Review

Microchip-based high-throughput screening analysis of combinatorial libraries

Journal

CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 6, Issue 3, Pages 359-366

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/S1367-5931(02)00323-X

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In recent years, there have been significant advances in biochemical assay miniaturization and integration of microchip-based technologies with combinatorial library screening for high-throughput and large-scale applications. Small-molecule microarrays, protein arrays and cell-based arrays and conventional DNA arrays as well as microfluidic approaches in HTS are discussed in this review.

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